For the full list of excipients, see section 6. Hyoscine hydrobromide for excess respiratory secretions 1. Cyclizine was not mutagenic in a full Ames test, including use of S9-microsomes but can nitrosate in vitro to form mutagenic products. Thank you, we just sent a survey email to confirm your preferences. Paediatric population Not licensed for use in children. The use of sedating antihistamines in the latter part of the third trimester may cause adverse effects in neonates such as irritability, paradoxical excitability, and tremor.
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Immune system disorders Not known Hypersensitivity reactions, including anaphylaxis have occurred. Can be very sedating at higher doses.
Cyclizine Lactate 50 mg/ml Injection
Valoid enhances the soporific effect of pethidine. Patient Platform Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Date of revision of the text. Injection site reactions including vein tracking, erythema, pain, thrombophlebitis and blisters.
Subcutaneous SC drug infusion by portable syringe driver has had a significant impact on pain management [ 1 ]. Sublingual administration is not always easy if the mouth is dry, co-ordination is poor or cognitive function is impaired.
Last updated on eMC: If the patient is not receiving oral syinge, mg per 24 hours, or total oral dose in mg in last 24 hours divided by 3. Most antihistamines are present in breast milk in varying amounts; although not known to be harmful, most manufacturers advise avoiding their use in mothers who are breast-feeding.
Cyclizine Lactate 50 mg/ml Injection – Summary of Product Characteristics (SmPC) – (eMC)
It may inhibit the part of the midbrain known collectively as the emetic centre. Although there are no data available, patients should be cautioned that Valoid may have additive effects with alcohol and other central nervous system depressants, e. In the management of acute overdosage with Valoid, gastric lavage and supportive measures for respiration and circulation fosage be performed if necessary. The exact mechanism by which cyclizine can prevent or suppress both nausea and vomiting from various causes is unknown.
I can’t leave without having something in place to take care of him. In this article arrow-down Setting up the syringe driver arrow-down Drugs used in the syringe driver arrow-down Drug compatibility arrow-down Problems with syringe drivers.
It allows the continuous delivery of a range of therapies to aid patient comfort. Breast-feeding Cyclizine is excreted in human milk, however, the amount has not been quantified.
Frequency not known Dsoage pain ; agranulocytosis ; angioedema ; anxiety ; apnoea ; appetite decreased ; arrhythmias ; asthenia ; syeinge ; constipation ; diarrhoea ; disorientation ; dizziness ; drowsiness ; dry mouth ; dry throat ; euphoric mood ; haemolytic anaemia ; hallucinations ; headache ; hepatic disorders ; hypertension ; hypotension ; increased gastric reflux ; insomnia ; leucopenia ; movement disorders ; muscle complaints ; nasal dryness ; nausea ; oculogyric crisis ; palpitations ; paraesthesia ; photosensitivity reaction ; seizure ; skin reactions ; speech dossge ; thrombocytopenia ; tinnitus ; tremor ; urinary retention ; vision blurred ; vomiting.
CYCLIZINE | Drug | BNF content published by NICE
Dosagw there are few compatibility problems with common two and three drug combinations containing:. As with other anticholinergic agents, Valoid may precipitate incipient glaucoma and it should be used with caution and appropriate monitoring in patients with glaucoma, urinary retention, obstructive disease of the gastrointestinal tract, hepatic disease, pheochromocytoma, hypertension, epilepsy and in males with possible prostatic hypertrophy.
Used in bowel spasm or ureteric colic.
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Also used as anticonvulsant. Palliative care for adults: The relevance of these studies to the human situation is not known.
By mouth, or by intravenous injection For Child 1 month—5 years 0. Hypersensitivity reactions, including anaphylaxis have occurred.
In such patients, cyclizine may cause a fall in cardiac output associated with increases in heart rate, mean arterial pressure and pulmonary wedge syronge. It does not produce more effective analgesia than the oral route unless the patient cannot use oral medication, or has serious compliance problems. For administration by mouthtablets may be crushed.